Accurate and Sensitive Quantification of Protein-DNA Binding Affinity...
academiccommons.columbia.edu
The model captures the specificity of p53 tetrameric binding sites and discovers multiple binding modes in a single sample. Additionally, we confirm that newly- identified low-affinity enhancer binding sites are functional in vivo, and that their contribution to gene expression matches their predicted affinity. Our results establish ...
The Biology of Nonspecific DNA Protein Interactions - Arnold Revzin -...
books.google.de
These studies did not, however, examine the effect of the different SSB binding modes. Furthermore, quantitative differences between the effects of the E. coli ...
OSA | Insight into the photo dynamic reaction of SNP and interaction...
opg.optica.org
Abstract. Sodium Nitroprusside (SNP) has been widely applied clinically as a vasodilator. The photo dynamic reaction of SNP, photo induced cleavage of supercoiled pBR322 DNA by SNP and the binding modes of SNP with human serum albumin (HSA) were investigated. © OSA. PDF Article ...
Spectroscopic and viscometric determination of DNA-binding modes of...
www.sciencedirect.com
DNA has different binding modes for non-covalent interactions with small molecules, where intercalation and minor groove binding are the most common ones [9].
Comparison of two different DMA-binding modes of the NF-κB p50...
www.nature.com
Analysis of the NF-κB p50 homodimer bound to different DNA sequences shows that the protein can recognize half-site spacings of either three or four base...
Alle Infos zum Namen "Binding Modes"
Binding modes of the precursor of adenovirus major core ...pubmed.ncbi.nlm.nih.gov › ...
pubmed.ncbi.nlm.nih.gov
Binding modes of the precursor of adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the ...
Using C-Trap® to unravel different binding modes of architectural ...lumicks.com › News
lumicks.com
· Using C-Trap® to unravel different binding modes of architectural DNA-binding proteins at different ionic conditions and DNA conformation.
Binding modes of methyllysine readers
mpmp.huji.ac.il
in regulating DNA-templated processes.While some PTMs directly modulate ...
Metals | Free Full-Text | Interaction and Binding Modes of...
www.mdpi.com
Interaction and Binding Modes of bis-Ruthenium(II) Complex to Synthetic DNAs. Hasi Rani Barai 1. , Dong Jin Lee 2. , Sung Wook Han 3.
Unusual DNA binding modes for metal anticancer complexes ...wrap.warwick.ac.uk › ...
wrap.warwick.ac.uk
... RDF+N3, Eprints Application Profile, OAI-PMH RIOXX. Pizarro, Ana M. and Sadler, P. J. (2009) Unusual DNA binding modes for metal anticancer complexes.
DNA binding modes of leukemia oncoproteins — Italian Ministry of...
moh-it.pure.elsevier.com
In this issue of Blood, Li et al expand our view on the mechanism of action of leukemia-associated oncoproteins and how they deregulate gene ...
PLOS Genetics: ELK1 Uses Different DNA Binding Modes to Regulate...
journals.plos.org
Author Summary One of the major outstanding questions in eukaryotic gene regulation is how transcription factors with seemingly very similar ...
Binding modes and pathway of RHPS4 to human telomeric G-quadruplex...
pubs.rsc.org
RHPS4, a potent binder to human telomeric DNA G-quadruplex, shows high efficacy in tumor cell growth inhibition. However, it's preferential binding to DNA G-quadruplex over DNA duplex (about 10 fold) remains to be improved toward its clinical application. A high resolution structure of the single-st.
Distinguishing binding modes of a new phosphonium dye with DNA by...
pubs.rsc.org
To understand the disruption of the cell processes induced by small molecule binding to DNA, numerous structural studies of DNA complexes have been done,...
Unraveling the physical chemistry and the mixed binding modes of...
pubs.rsc.org
Single molecule stretching experiments were performed with complexes formed between a DNA binding drug that exhibits multiple mixed binding modes ...
On the binding modes of metal NHC complexes with DNA secondary...
orca.cardiff.ac.uk
Abstract. Organometallic compounds currently occupy an important place in the field of medicinal inorganic chemistry due to the unique chemical properties of metal coordination compounds. Particularly, metal compounds ligated by N-heterocyclic carbenes (NHC) have shown high potential for biomedical ...
Physical Organization of DNA by Multiple Non-Specific DNA-Binding...
journals.plos.org
· These binding modes are controlled by conditions such as protein, monovalent salt, and magnesium concentrations. Our results have important ...
Distinctive Cognate Sequence Discrimination, Bound DNA ...ri.conicet.gov.ar › handle
ri.conicet.gov.ar
Distinctive Cognate Sequence Discrimination, Bound DNA Conformation, and Binding Modes in the E2 C-Terminal Domains from Prototype Human and Bovine ...
"Sequence and topological specificity in the binding of...
nsuworks.nova.edu
Binding constants for binding to salmon sperm DNA, obtained from uv titrations, are similar [circa 3 x 104 at 25 C]. Optical titration vs. temperature studies and isothermal calorimetry results suggest that the isomers bind with different enthalpies. The combined results of these studies demonstrate that the binding modes and ...
Microscopic modes and free energies for topoisomerase I-DNA ...www.infona.pl › resource
www.infona.pl
The detailed binding structures and binding free energies for the Topo1-DNA complex ... The detailed binding modes and the crucial factors affecting the binding free energies ... Copyright owner:Springer-Verlag Berlin Heidelberg,
Molecular Mechanisms of DNA-Protein Interaction - Paul Modrich
grantome.com
Mismatch repair plays a major role in genome stabilization, and available information indicates that the substrate specificity and mechanism of the repair...
Binding configurations of single-stranded DNA binding protein and...
www.ideals.illinois.edu
Cells have evolved single-stranded DNA binding (SSB) proteins to wrap and protect this ssDNA. In E. coli, SSB is known to wrap ssDNA in a variety of binding configurations, or modes. Three different binding modes, (SSB)65, (SSB)56, and (SSB)35, which wraps 65, 56, and 35 nucleotides (nt) respectively, ...
Methylene Blue Binding to DNA with Alternating GC Base Sequence: A...
www.semanticscholar.org
Medizin, Robert-Ro¨, D Berlin, Germany, Laboratoire de Biochimie The´orique ... There are three main DNA binding modes for the dye: (i).
Relationship between the photoinduced electron transfer and binding...
pubs.rsc.org
The binding modes of a pyrene–porphyrin dyad, (1-pyrenyl)-tris(N-methyl-p- pyridino)porphyrin (PyTMpyP), to DNA and its photophysical properties have been investigated using various spectroscopic techniques. The circular dichroism (CD) spectrum of PyTMpyP bound to DNA (PyTMpyP–DNA) showed one negative and ...
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Zapart W., Zapart M. B. , Nesterenko N. M.. EFFECT OF Li-DOPING ON THE FERROELASTIC PHASE TRANSITIONS IN KSc(MoO4)2. "The 13th International Meeting on Ferroelectricity (IMF-13)" Польша, Kraków Spectroscopic studies on competition between two DNA-Quinacrine binding modes. "XXI International ...
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