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SHOC of the new: Targeting SHOC2 in RAS mutant cancers | UCL Cancer...
www.ucl.ac.uk
UCL-led research has identified a promising target that could open up new ways to tackle some of the most common cancers.
Science Journals — AAASwww.einstein.yu.edu › events › Ren_JC_
www.einstein.yu.edu
in human K-RAS lung AC tissue, confirming the implication of other non-EGFR ERBB family members in K-RAS–mutated lung tumori- genesis ...
Bücher
Inflammation and Lung Cancer - Google Books
books.google.de
... or other eicosanoids produced by inflammatory cells play the same role in K-Ras lung tumor vis a vis and EGFR-mutant lung tumor. Approaches using ...
Inhibitors of the Ras Superfamily G-proteins, Part B - Google Books
books.google.com.ua
Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss...
Molecular Pathology of Lung Diseases - Google Books
books.google.de
Molecular Pathology of Lung Diseases, the first volume in the Molecular Pathology Library Series under the series editorship of Philip T. Cagle, MD provides a...
Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General...
books.google.de
... and RALB significantly reduced tumor burden, which clearly establishes that K-Ras lung tumors strongly depend on Ral G-protein signaling (Peschard et al.
Dokumente zum Namen
Cancers | Special Issue : Lung Cancer
www.mdpi.com
Cancers, an international, peer-reviewed Open Access journal.
Targeting of Cancer Stem Cells and Their Microenvironment in...
apps.dtic.mil
The overall goal of this proposal is to understand the role of the Hh pathway in the maintenance and proliferation of lungadenocarcinoma progenitor cells and...
Wissenschaftliche Veröffentlichungen
Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation |...
molecular-cancer.biomedcentral.com
The results showed that the protein levels of c-Myc, c-Jun and p21 were not considerably changed in Hdac7 +/− /K-Ras lung tumors compared ...
The aging lung: tissue telomere shortening in health and disease |...
respiratory-research.biomedcentral.com
). c: RTL in mildly versus severely affected RAS lung tissue (both n = 28), stratified based on surface density of core micro CT (p = ).
Veröffentlichungen allgemein
Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation |...
link.springer.com
Background Lung cancer is the leading cause of cancer death worldwide. However, the molecular mechanisms underlying lung cancer development have not been fully...
Interactions between wild-type and mutant Ras genes in lung and skin...
app.dimensions.ai
Re-imagining discovery and access to research: grants, datasets, publications, citations, clinical trials, patents and policy documents in one place.
K-Ras protein as a drug target | SpringerLink
link.springer.com
K-Ras proteins are major drivers of human cancers, playing a direct causal role in about one million cancer cases/year. In cancers driven by mutant K-Ras,
Artikel & Meinungen
Taking Food Away - NCI
www.cancer.gov
Cancers driven by mutant KRAS genes are more dependent on scavenging nutrients from the tumor microenvironment, via macropinocytosis, and from internal...
Sonstiges
Cla-ras / Lung Cycles - s/t
varioussmallflames.co.uk
Various Small Flames review the self-titled split cassette from Cla-ras and Lung Cycles, out now on Lily Tapes and Discs and available via Bandcamp.
Nullifying the CDKN2AB Locus Promotes Mutant K-ras Lung Tumorigenesis...
www.semanticscholar.org
UNLABELLED Lung cancer commonly displays a number of recurrent genetic abnormalities, and about 30% of lung adenocarcinomas carry activating ...
ARAF | Cancer Genetics Web
cancer-genetics.org
In addition, studies in xenograft and K-Ras lung cancer mouse models demonstrated that genetic deletion or pharmacological suppression of CypD efficiently prevented Ras-dependent tumor formation. Furthermore, Erbb2-mediated breast tumorigenesis was similarly prevented by targeting CypD. From a mechanistic point of view, CypD expression was associated with a reduced …
2014 Lung Cancer Highlight - Deconstruction of Oncogenic K-RAS...
cdmrp.health.mil
Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Molecular Cancer Research 12(6): Clinical Trial
Cancers | Free Full-Text | Targeting of Both the c-Met and EGFR...
www.mdpi.com
... K-ras lung tumors. This was not observed with combination treatment. A small molecule c-Met inhibitor decreased formation of both K-ras wild-type and mutant ...
A quantitative and multiplexed approach to uncover the fitness...
experiments.springernature.com
Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Mol. Cancer Res. 12 , 912–923 (2014). Ho, V.M., Schaffer, B.E., ...
Diacylglycerol kinase n modualtes oncogenic properties of lung cancer...
pesquisa.bvsalud.org
We determined the expression levels of DGKη in a mouse models of mutant EGFR and K-Ras lung cancer and in human lung cancer cell lines with activating ...
Fluorescence background subtraction technique for hybrid fluorescence...
www.spiedigitallibrary.org
In Vivo Study of K-ras Lung Tumor Model. In young, four-week-old K-ras mice, tumor targets were around 0.8 mm, which is close to the ...
Lung cancer initiating cells in a tumor mouse model deficient in...
grantome.com
Schuster, Katja; Venkateswaran, Niranjan; Rabellino, Andrea et al. (2014) Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Mol Cancer ...
Notch1 Regulates Tumor Formation, Possible Lung Cancer Target
www.cancernetwork.com
“Taken together, our findings indicate that loss of Notch1 significantly reduced K-ras lung tumor initiation and overall tumor burden,” the ...
[PDF] PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung...
www.semanticscholar.org
Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Katja Schuster, Niranjan Venkateswaran, +3 authors Pier Paolo Scaglioni. Molecular ...
Tumor Cell Dependence on Host Metabolism - Eileen White - Grantomegrantome.com › grant › NIH › R01-CA
grantome.com
Specifically, we will address the role of host metabolism in mouse models of K-Ras lung cancer, and B-Raf lung cancer and melanoma: Aim 1 : Identify the ...
Cla-Ras/Lung Cycles reviews, music, news - sputnikmusic
www.sputnikmusic.com
Album reviews, biography and music news for Cla-Ras/Lung Cycles at sputnikmusic
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