Ras Lung und K-Ras - Info zur Person - Personensuche Yasni.de

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Science Journals — AAASwww.einstein.yu.edu › events › Ren_JC_

www.einstein.yu.edu

in human K-RAS lung AC tissue, confirming the implication of other non-EGFR ERBB family members in K-RAS–mutated lung tumori- genesis ...

Inflammation and Lung Cancer - Google Books

books.google.de

... or other eicosanoids produced by inflammatory cells play the same role in K-Ras lung tumor vis a vis and EGFR-mutant lung tumor. Approaches using ...

Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General...

books.google.de

... and RALB significantly reduced tumor burden, which clearly establishes that K-Ras lung tumors strongly depend on Ral G-protein signaling (Peschard et al.

Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation |...

molecular-cancer.biomedcentral.com

The results showed that the protein levels of c-Myc, c-Jun and p21 were not considerably changed in Hdac7 +/− /K-Ras lung tumors compared ...

K-Ras protein as a drug target | SpringerLink

link.springer.com

K-Ras proteins are major drivers of human cancers, playing a direct causal role in about one million cancer cases/year. In cancers driven by mutant K-Ras,

Nullifying the CDKN2AB Locus Promotes Mutant K-ras Lung Tumorigenesis...

www.semanticscholar.org

UNLABELLED Lung cancer commonly displays a number of recurrent genetic abnormalities, and about 30% of lung adenocarcinomas carry activating ...

ARAF | Cancer Genetics Web

cancer-genetics.org

In addition, studies in xenograft and K-Ras lung cancer mouse models demonstrated that genetic deletion or pharmacological suppression of CypD efficiently prevented Ras-dependent tumor formation. Furthermore, Erbb2-mediated breast tumorigenesis was similarly prevented by targeting CypD. From a mechanistic point of view, CypD expression was associated with a reduced …

2014 Lung Cancer Highlight - Deconstruction of Oncogenic K-RAS...

cdmrp.health.mil

Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Molecular Cancer Research 12(6): Clinical Trial

Cancers | Free Full-Text | Targeting of Both the c-Met and EGFR...

www.mdpi.com

... K-ras lung tumors. This was not observed with combination treatment. A small molecule c-Met inhibitor decreased formation of both K-ras wild-type and mutant ...

A quantitative and multiplexed approach to uncover the fitness...

experiments.springernature.com

Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Mol. Cancer Res. 12 , 912–923 (2014). Ho, V.M., Schaffer, B.E., ...

Diacylglycerol kinase n modualtes oncogenic properties of lung cancer...

pesquisa.bvsalud.org

We determined the expression levels of DGKη in a mouse models of mutant EGFR and K-Ras lung cancer and in human lung cancer cell lines with activating ...

Fluorescence background subtraction technique for hybrid fluorescence...

www.spiedigitallibrary.org

In Vivo Study of K-ras Lung Tumor Model. In young, four-week-old K-ras mice, tumor targets were around 0.8 mm, which is close to the ...

Lung cancer initiating cells in a tumor mouse model deficient in...

grantome.com

Schuster, Katja; Venkateswaran, Niranjan; Rabellino, Andrea et al. (2014) Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Mol Cancer ...

Notch1 Regulates Tumor Formation, Possible Lung Cancer Target

www.cancernetwork.com

“Taken together, our findings indicate that loss of Notch1 significantly reduced K-ras lung tumor initiation and overall tumor burden,” the ...

[PDF] PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung...

www.semanticscholar.org

Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis. Katja Schuster, Niranjan Venkateswaran, +3 authors Pier Paolo Scaglioni. Molecular ...

Tumor Cell Dependence on Host Metabolism - Eileen White - Grantomegrantome.com › grant › NIH › R01-CA

grantome.com

Specifically, we will address the role of host metabolism in mouse models of K-Ras lung cancer, and B-Raf lung cancer and melanoma: Aim 1 : Identify the ...

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